Antibiotics

The highest quality

The production of antibiotics is a principal application of the BHS rotary pressure filter (type RPF). In addition, the indexing belt filter (type BF) and Autopress (type AP) from BHS are available for special applications.

Our state-of-the-art filter systems meet GMP, CIP and Atex requirements. All three systems can be validated and are manufactured in compliance with highly demanding quality guidelines. They address applications such as manufacturing intermediates or generating active substances. Suspensions are processed in closed and inert systems. Absolute purity of the final product and consistent quality are thus ensured. Depending on the production process, our filters are operated in a continuous process (belt filter) or batch operation (Autopress).

Online contact request
Verify your details
Verify your details

Downloads

Brochure "Indexing belt filter (BF)" (PDF / 1.2 MB)
Brochure "Indexing belt filter (BF)"

Product brochure for indexing belt filter (BF) as a continuously operating, horizontal vacuum filter

Size: 1.2 MB
“Rotary pressure filter (RPF)” brochure (PDF / 1.4 MB)
“Rotary pressure filter (RPF)” brochure

Product brochure for the rotary pressure filter (RPF)

Size: 1.4 MB
Technical data sheet “Rotary pressure filter (RPF)” (PDF / 94 KB)
Technical data sheet “Rotary pressure filter (RPF)”

Technical data for rotary pressure filter (RPF)

Size: 94 KB
Technical data sheet “Indexing belt filter (BF)” (PDF / 102 KB)
Technical data sheet “Indexing belt filter (BF)”

Technical data on the indexing belt filter (BF) as a continuously operating, horizontal vacuum filter

Size: 102 KB
Technical data sheet “Autopress (AP)” (PDF / 80 KB)
Technical data sheet “Autopress (AP)”

Technical data on Autopress (AP)

Size: 80 KB

Advantages of BHS filtration technology

  • Machine designs compliant with quality regulations
  • Conformance to the highest product requirements
  • Best possible product quality with optimal, consistent performance
  • Gentle product handling
  • Batch or continuous operation
  • Trained service team

Applications

  • Broad-spectrum antibiotics
  • Penicillin
  • 6 APA
  • 7 ADC
  • Amoxicillin
  • Cephalosporin

BHS filtration technical center

Link to tests at BHS technical center

Technical article

Thin-cake filtration technology to meet full containment for air-sensitive and toxic chemical and pharmaceutical production

PharmaChem
1/2 2016 (January/February)
February 2016
PDF (3.5 MB)
Thin-cake filtration technology to meet full containment for air-sensitive and toxic chemical and pharmaceutical production

In many chemical and pharmaceutical processes, solid-liquid separation, cake washing and drying steps directly impact the effectiveness of the production operation. Further complicating these operations is the nature of the process and especially if the process is air-sensitive or toxic. This article discusses the choice of thin-cake (2-25 mm) pressure separation technology for full containment, no residual heel and their benefits to optimizing the effectiveness of the production process. For full containment, the paper then continues with a discussion of clean-in-place operations to meet current Good Manufacturing Practices (cGMP) guidelines including riboflavin test, validations and ANSI/ISA S88 and IEC 61512-1 batch process control systems.

Size: 3.5 MB

A Review of Filter Press Basics Versus Alternative Technologies

PharmaChem
Mai 2008 - 33
May 2008
PDF (323 KB)
A Review of Filter Press Basics Versus Alternative Technologies

Filtration experts, over the years, have discussed and debated filter presses and have indicated that soon they would be a thing of the past; the last filter press would be replaced by more modern equipment. Given that filter presses were amongst the oldest mechanical dewatering devices, this was a fairly plausible suggestion. However, now, almost half a century later, any chemical engineering exhibition shows that filter presses are alive and well and are going to be around for years to come. True, they look different from the ones in the 1950’s, but essentially they are still the same device. Their continued presence is a tribute to the filter press manufacturers who embraced new materials and upgraded the mechanics and configurations. However, the basics are still the same and much of the issues surrounding filter presses remain valid.

Size: 323 KB

Process Testing and Scale-UP for a BHS Pharma Rotary Pressure Filter as a Replacement for Two Inverting-Basket Centrifuges at a Bulk Pharmaceutical Manufacturing Facility

BHS-Filtration Inc.
Report Number F-1079-03
October 2003
PDF (405 KB)
Process Testing and Scale-UP for a BHS Pharma Rotary Pressure Filter as a Replacement for Two Inverting-Basket Centrifuges at a Bulk Pharmaceutical Manufacturing Facility

The BHS Ph-RPF technology provides improved product quality with more efficient washing ratios compared with the inverting-basket centrifuges. Savings in solvent usage, energy consumption, maintenance costs and capital and installation costs result in overall project savings on the order of 4-6 to 1.

Size: 405 KB
OK
We use cookies in order to adapt the website to the requirements of our visitors in the best possible way. The use of our website indicates your agreement to having cookies stored on your computer. Data privacy