Antibiotics

The highest quality

The manufacture of antibiotics is a primary application for two types of BHS filters: Autopress (type AP) and indexing belt filters (type BF). Our filter systems are state of the art and meet GMP, CIP and ATEX requirements. Both systems can be validated and are manufactured under the strictest quality guidelines. These filters are used in the manufacture of intermediate products and in the preparation of drugs. Suspensions are processed in closed and inerted systems. This ensures that the final product is absolutely pure and that product quality is consistently high. Depending on the production scenario, our filters can be used in a continuous process (belt filter) or in a batch process (Autopress).

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Brochure "Belt filter" (PDF / 1.1 MB)
Brochure "Belt filter"

Product brochure "Belt filter" (BF)

Size: 1.1 MB
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Brochure "Autopress" (PDF / 1.2 MB)
Brochure "Autopress"

Product brochure "Autopress (AP)"

Size: 1.2 MB
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Advantages of BHS filtration technology

  • Machine designs compliant with quality regulations
  • Conformance to the highest product requirements
  • Best possible product quality with optimal, consistent performance
  • Gentle product handling
  • Batch or continuous operation
  • Trained service team

Applications

  • Broad-spectrum antibiotics
  • Penicillin
  • 6 APA
  • 7 ADC
  • Amoxicillin
  • Cephalosporin

BHS filtration technical center

Link to tests at BHS technical center

Technical article

A Review of Filter Press Basics Versus Alternative Technologies

Mai 2008 - 33
May 2008
PDF (323 KB)
A Review of Filter Press Basics Versus Alternative Technologies

Filtration experts, over the years, have discussed and debated filter presses and have indicated that soon they would be a thing of the past; the last filter press would be replaced by more modern equipment. Given that filter presses were amongst the oldest mechanical dewatering devices, this was a fairly plausible suggestion. However, now, almost half a century later, any chemical engineering exhibition shows that filter presses are alive and well and are going to be around for years to come. True, they look different from the ones in the 1950’s, but essentially they are still the same device. Their continued presence is a tribute to the filter press manufacturers who embraced new materials and upgraded the mechanics and configurations. However, the basics are still the same and much of the issues surrounding filter presses remain valid.

Size: 323 KB
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Process Testing and Scale-UP for a BHS Pharma Rotary Pressure Filter as a Replacement for Two Inverting-Basket Centrifuges at a Bulk Pharmaceutical Manufacturing Facility

Report Number F-1079-03
October 2003
PDF (405 KB)
Process Testing and Scale-UP for a BHS Pharma Rotary Pressure Filter as a Replacement for Two Inverting-Basket Centrifuges at a Bulk Pharmaceutical Manufacturing Facility

The BHS Ph-RPF technology provides improved product quality with more efficient washing ratios compared with the inverting-basket centrifuges. Savings in solvent usage, energy consumption, maintenance costs and capital and installation costs result in overall project savings on the order of 4-6 to 1.

Size: 405 KB
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